Open Systems Pharmacology

--coat West- Luxe 3 -nagi X Hika ~upd~ Jun 2026

Reliable, powerful and easy-to-use modeling & simulation tools for pharmaceutical and other life-sciences applications. Qualified and accepted by the scientific community including academia, regulatory agencies and industry. Available free to everyone.

Essentials

Download OSP Suite

Explore the full functionality of the OSP suite. PBPK, PBPK/PD, QSP – the OSP Suite gives you the flexibility to build it all without having to start from scratch.

Forum

Have your questions answered or provide answers to others. The Forum is a great way to stay up-to-date on the community buzz around OSP.

Documentation

Need to find out how to use a feature? Looking to understand the inner workings of the model? Here you’ll find the extensive OSP manual and qualification documents.

News & Release

Save the Date: OSP Community Conference 2026

In Beerse, Antwerp September 24th and 25th

Open Systems Pharmacology Suite - Version 12 Update 2

We are pleased to announce the new release of the OSP Suite Version 12 Update 2 which is now available for download.

WORKSHOP AT ACOP COLORADO.

Join ESQlabs at the ACoP Conference in Colorado Building Scalable PBPK-QSP Models - Modularization in MoBi for OSP Suite V12.

Ready to take the plunge? Download

The collaboration represents a high-profile intersection of streetwear and luxury design. This limited-edition release features a partnership between the experimental Japanese label Nagi and the avant-garde aesthetic of Hika, debuting under the prestigious "Luxe" series from COAT West . Overview of the Luxe 3 Collection

For Nagi, it solidified his status as a top-tier performer capable of carrying high-stakes scenes. For Hika, it showcased his versatility as a scene partner who could elevate the performance of those around him. Together, they created a piece of work that transcends the typical boundaries of the genre, remaining a fan-favorite for its palpable heat and undeniable aesthetic beauty.

As of late 2023, both Nagi and Hika have stepped back from active performing, making a time capsule piece. Rumors suggest Nagi has moved into fashion modeling (his walk in the film’s opening sequence got him noticed by a Japanese streetwear brand), while Hika is rumored to be training in choreography.

The Luxe 3 collection by COAT WEST, Nagi X Hika is a game-changing collaboration that redefines the fashion landscape. With its bold, innovative designs and commitment to artistic expression, this collection is sure to inspire fashion enthusiasts and art lovers alike.

Provides windproofing without the traditional "crunchy" feel. Adaptive Silhouette:

The Luxe 3 - nagi X Hika collection features several standout pieces that are sure to turn heads. Some of the key items include:

Publications & Models

Models

Glucose Insulin Model

Scientifically exciting for diabetes researchers. Technically exciting for everyone with PBPK models of glucose, insulin, and glucagon coupled through non-mechanistic PD as well as systems pharmacology PD models.

Publications

Journal Publications

Growing list of scientific journal publications that relates to OSP or describes work with PK-Sim® or MoBi®. Add your own contributions and label them or others appropriately to further grow and structure this database.

Take a look at all our models Browse

--coat West- Luxe 3 -nagi X Hika ~upd~ Jun 2026

The collaboration represents a high-profile intersection of streetwear and luxury design. This limited-edition release features a partnership between the experimental Japanese label Nagi and the avant-garde aesthetic of Hika, debuting under the prestigious "Luxe" series from COAT West . Overview of the Luxe 3 Collection

For Nagi, it solidified his status as a top-tier performer capable of carrying high-stakes scenes. For Hika, it showcased his versatility as a scene partner who could elevate the performance of those around him. Together, they created a piece of work that transcends the typical boundaries of the genre, remaining a fan-favorite for its palpable heat and undeniable aesthetic beauty. --COAT WEST- Luxe 3 -nagi X Hika

As of late 2023, both Nagi and Hika have stepped back from active performing, making a time capsule piece. Rumors suggest Nagi has moved into fashion modeling (his walk in the film’s opening sequence got him noticed by a Japanese streetwear brand), while Hika is rumored to be training in choreography. For Hika, it showcased his versatility as a

The Luxe 3 collection by COAT WEST, Nagi X Hika is a game-changing collaboration that redefines the fashion landscape. With its bold, innovative designs and commitment to artistic expression, this collection is sure to inspire fashion enthusiasts and art lovers alike. Rumors suggest Nagi has moved into fashion modeling

Provides windproofing without the traditional "crunchy" feel. Adaptive Silhouette:

The Luxe 3 - nagi X Hika collection features several standout pieces that are sure to turn heads. Some of the key items include:

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