Epidermal Nerve Fiber Density (ENFD) Testing - Bako Diagnostics
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The counts sit near the lower limit of normal distribution, often indicating early-stage degeneration or tracking localized, non-symmetrical nerve damage. In a healthy individual, these nerve fibers innervate
In a healthy individual, these nerve fibers innervate the epidermis (the top layer of the skin). However, in patients with SFPN, these terminal nerve endings begin to disintegrate and die off, resulting in the classic "stocking-and-glove" distribution of neuropathic pain. By counting the number of nerve fibers per millimeter of epidermal length, clinicians can definitively diagnose SFPN, track disease progression, or even measure nerve regeneration over time. The Biopsy Procedure: What to Expect
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